Late-stage kidney disease or chronic renal failure sometimes causes intense itching skin. A research found that 42% of dialysis patients experienced moderate to severe itching.
Itchy skin all over could potentially be a subtle indicator of liver disease. In kidney disease, itching is a late symptom, but it's an early sign of liver disease.
If your fingernails leave thin, raised red welts after softly scratching your skin, you may have dermatographia or dermatographism, a kind of persistent hives.
Chronic itching in the upper middle back (without a rash) can be a symptom of nerve dysfunction. Spinal cord illness must be ruled out before treatment.
Itchy lumps or blisters on knees, elbows, buttocks, and/or hairline may indicate dermatitis herpetiformis (DH), a celiac disease skin symptom.
Itchiness with or without a rash is a symptom of Hodgkin's disease, possibly produced by cytokines, which promote inflammation in response to infection.
Overactive or underactive thyroid might cause skin weirdness. Changes in sweat glands may induce skin dryness, but no one knows why.
Allergies are a prevalent chronic illness. Many skin allergies are classed as contact dermatitis, an itchy rash caused by allergen interaction.
Menopause can cause dry, itchy skin. Loss of estrogen, a collagen-building ingredient, causes thinner, itchier skin.
Paget's disease of the nipple is an extremely rare form of breast cancer. Scaly, itchy patches appear around the nipple and areola.